disease

nmosd

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about nmosd: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

55Connections
0Hypotheses
0Analyses
22Outgoing
11Incoming

No summary available yet. View on Wiki →

Disease Info
Associated GenesTREM2
KG Connections33 knowledge graph edges
DatabasesOMIMOrphanetClinicalTrialsPubMed

Wiki Pages (20)

Knowledge base pages for this entity

Multiple Sclerosis (MS)

disease · 3824 words

Demyelination

mechanism · 3212 words

Neuromyelitis Optica Spectrum Disorder (NMOSD)

disease · 3198 words

Diseases

index · 3070 words

Glymphatic System in Neurodegeneration

mechanism · 2768 words

Pathway Diagram

graph TD
    nmosd["<b>nmosd</b>"]
    AQP4["AQP4"]
    nmosd -->|"associated with"| AQP4
    disease["disease"]
    nmosd -->|"inhibits"| disease
    AQP4["AQP4"]
    nmosd -->|"regulates"| AQP4
    AQUAPORIN_4["AQUAPORIN-4"]
    nmosd -->|"regulates"| AQUAPORIN_4
    MULTIPLE_SCLEROSIS["MULTIPLE SCLEROSIS"]
    nmosd -->|"associated with"| MULTIPLE_SCLEROSIS
    AQP4["AQP4"]
    nmosd -->|"interacts with"| AQP4
    AQUAPORIN_4["AQUAPORIN-4"]
    nmosd -->|"interacts with"| AQUAPORIN_4
    MULTIPLE_SCLEROSIS["MULTIPLE SCLEROSIS"]
    nmosd -->|"interacts with"| MULTIPLE_SCLEROSIS
    Oligodendrocyte["Oligodendrocyte"]
    nmosd -->|"interacts with"| Oligodendrocyte
    MYELIN["MYELIN"]
    nmosd -->|"interacts with"| MYELIN
    disease["disease"]
    nmosd -->|"interacts with"| disease
    Spinal_Cord["Spinal Cord"]
    nmosd -->|"interacts with"| Spinal_Cord
    Autoimmune["Autoimmune"]
    nmosd -->|"interacts with"| Autoimmune
    AQP4["AQP4"]
    nmosd -->|"activates"| AQP4
    CENTRAL_NERVOUS_SYSTEM["CENTRAL NERVOUS SYSTEM"]
    nmosd -->|"activates"| CENTRAL_NERVOUS_SYSTEM
    microglia["microglia"]
    nmosd -->|"regulates"| microglia
    MYELIN["MYELIN"]
    nmosd -->|"regulates"| MYELIN
    DEMYELINATION["DEMYELINATION"]
    nmosd -->|"regulates"| DEMYELINATION
    microglia["microglia"]
    nmosd -->|"activates"| microglia
    Macrophage["Macrophage"]
    nmosd -->|"activates"| Macrophage
    MICROGLIAL_ACTIVATION["MICROGLIAL ACTIVATION"]
    nmosd -->|"activates"| MICROGLIAL_ACTIVATION
    microglia["microglia"]
    nmosd -->|"interacts with"| microglia
    mogad["mogad"]
    mogad -->|"associated with"| nmosd
    mogad["mogad"]
    mogad -->|"interacts with"| nmosd
    mogad["mogad"]
    mogad -->|"regulates"| nmosd
    late["late"]
    late -->|"activates"| nmosd
    Neuroinflammation["Neuroinflammation"]
    Neuroinflammation -->|"regulates"| nmosd
    TREM2["TREM2"]
    TREM2 -->|"regulates"| nmosd
    TREM2["TREM2"]
    TREM2 -->|"activates"| nmosd
    TREM2["TREM2"]
    TREM2 -->|"associated with"| nmosd

Outgoing (28)

TargetRelationTypeStr
AQP4associated_withgene0.50
AQP4regulatesgene0.50
AQP4interacts_withgene0.50
AQP4activatesgene0.50
diseaseinhibitsdisease0.50

Incoming (27)

SourceRelationTypeStr
mogadassociated_withdisease0.50
mogadinteracts_withdisease0.50
mogadregulatesdisease0.50
lateactivatesdisease0.50
TREM2regulatesgene0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found