Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about mogad: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
MOGAD["MOGAD"]
MOGAD -->|"involved_in"| Demyelinating_Disease["Demyelinating Disease"]
MOGAD -->|"involved_in"| Demyelination["Demyelination"]
MOGAD -->|"correlates_with"| Multiple_Sclerosis["Multiple Sclerosis"]
MOGAD -->|"treats"| NMOSD["NMOSD"]
MOGAD -->|"interacts"| nmosd["nmosd"]
MOG["MOG"] -.biomarker for.-> MOGAD
DEMYELINATION["DEMYELINATION"] -->|"involved_in"| MOGAD
MRI_Lesions["MRI Lesions"] -.biomarker for.-> MOGAD
AQP4["AQP4"] -->|"treats"| MOGAD
AQUAPORIN_4["AQUAPORIN-4"] -->|"treats"| MOGAD| Target | Relation | Type | Str |
|---|---|---|---|
| nmosd | associated_with | disease | 0.50 |
| AQP4 | associated_with | gene | 0.50 |
| nmosd | interacts_with | disease | 0.50 |
| AQP4 | interacts_with | gene | 0.50 |
| nmosd | regulates | disease | 0.50 |
| AQP4 | regulates | gene | 0.50 |
| MULTIPLE SCLEROSIS | associated_with | disease | 0.50 |
| AQUAPORIN-4 | interacts_with | gene | 0.50 |
| MULTIPLE SCLEROSIS | interacts_with | disease | 0.50 |
| Oligodendrocyte | interacts_with | cell_type | 0.50 |
| MYELIN | interacts_with | concept | 0.50 |
| disease | interacts_with | disease | 0.50 |
| Autoimmune | interacts_with | disease | 0.50 |
| GRP78 | inhibits | protein | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| MOG | biomarker_for | protein | 0.95 |
| MYELIN OLIGODENDROCYTE GLYCOPROTEIN | associated_with | entity | 0.95 |
| MOG | associated_with | protein | 0.95 |
| DEMYELINATION | involved_in | entity | 0.95 |
| MRI Lesions | biomarker_for | biomarker | 0.90 |
| Multiple Sclerosis | associated_with | disease | 0.80 |
| AQP4 | associated_with | entity | 0.60 |
| AQP4 | treats | entity | 0.60 |
| AQP4 | regulates | entity | 0.60 |
| AQUAPORIN-4 | treats | entity | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||