Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Parthanatos: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | Parthanatos |
| Summary | Page for Parthanatos in Neurodegeneration |
| Related Diseases | Neuron Loss, PARKINSON'S DISEASE, ALZHEIMER'S DISEASE, ALS, Parkinson'S Disease |
Knowledge base pages for this entity
graph TD
Parthanatos["Parthanatos"] -->|"contributes to"| Neuron_Loss["Neuron Loss"]
style Neuron_Loss fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Parthanatos["Parthanatos"] -->|"contributes to"| Neuroinflammation["Neuroinflammation"]
style Neuroinflammation fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Parthanatos["Parthanatos"] -->|"causes"| NEURON["NEURON"]
style NEURON fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
Parthanatos["Parthanatos"] -->|"involved in"| PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
style PARKINSON_S_DISEASE fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
Parthanatos["Parthanatos"] -->|"involved in"| ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
style ALZHEIMER_S_DISEASE fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
Parthanatos["Parthanatos"] -->|"involved in"| ALS["ALS"]
style ALS fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
Parthanatos["Parthanatos"] -->|"involved in"| Huntington_s_Disease["Huntington's Disease"]
style Huntington_s_Disease fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
PARP_1["PARP-1"] -->|"mediates"| Parthanatos["Parthanatos"]
style PARP_1 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
AIF["AIF"] -->|"mediates"| Parthanatos["Parthanatos"]
style AIF fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
PARP1["PARP1"] -->|"involved in"| Parthanatos["Parthanatos"]
style PARP1 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
MIF["MIF"] -->|"mediates"| Parthanatos["Parthanatos"]
style MIF fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
Parp1_Inhibitors["Parp1 Inhibitors"] -.->|"inhibits"| Parthanatos["Parthanatos"]
style Parp1_Inhibitors fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
style Parthanatos fill:#1b5e20,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold| Target | Relation | Type | Str |
|---|---|---|---|
| Neuron Loss | contributes_to | phenotype | 0.95 |
| Neuroinflammation | contributes_to | process | 0.95 |
| NEURON | causes | cell_type | 0.95 |
| NEUROINFLAMMATION | mediates | process | 0.95 |
| PARKINSON'S DISEASE | involved_in | disease | 0.95 |
| ALZHEIMER'S DISEASE | involved_in | disease | 0.95 |
| ALS | involved_in | disease | 0.95 |
| Parkinson'S Disease | involved_in | disease | 0.95 |
| Alzheimer'S Disease | involved_in | disease | 0.95 |
| Parkinson's Disease | involved_in | disease | 0.90 |
| Alzheimer's Disease | involved_in | disease | 0.90 |
| Huntington's Disease | involved_in | disease | 0.90 |
| Amyotrophic Lateral Sclerosis | involved_in | disease | 0.90 |
| Stroke | involved_in | disease | 0.90 |
| Huntington'S Disease | involved_in | disease | 0.90 |
| Cell Death | mediates | process | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||