Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PGS1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Name | PGS1 |
| Key Genes/Proteins | LYRM7, CD14, BCS1L, MRPS31, MITOCHONDRIA, AND |
| Related Diseases | Septic Cardiomyopathy, Als, Cardiovascular, ALS, Inflammation |
graph TD
PGS1["PGS1"]
PGS1 -.biomarker for.-> Septic_Cardiomyopathy["Septic Cardiomyopathy"]
PGS1 -->|"target for"| Als["Als"]
PGS1 -->|"target for"| B_Cell["B Cell"]
PGS1 -->|"target for"| Rb["Rb"]
PGS1 -->|"target for"| App["App"]
CD14["CD14"] -->|"target for"| PGS1| Target | Relation | Type | Str |
|---|---|---|---|
| Septic Cardiomyopathy | biomarker_for | disease | 0.85 |
| Als | therapeutic_target | disease | 0.65 |
| Cardiovascular | associated_with | disease | 0.65 |
| ALS | associated_with | disease | 0.65 |
| Inflammation | associated_with | disease | 0.65 |
| Cardiomyopathy | associated_with | disease | 0.65 |
| Als | associated_with | disease | 0.65 |
| LYRM7 | associated_with | gene | 0.60 |
| CD14 | associated_with | gene | 0.60 |
| BCS1L | associated_with | gene | 0.60 |
| MRPS31 | associated_with | gene | 0.60 |
| MITOCHONDRIA | associated_with | gene | 0.60 |
| AND | associated_with | gene | 0.60 |
| HUB GENES | associated_with | gene | 0.60 |
| FBXO7 | associated_with | gene | 0.60 |
| IMMUNE INFILTRATION | associated_with | gene | 0.60 |
| B Cell | associated_with | cell_type | 0.60 |
| TIMMDC1 | associated_with | gene | 0.60 |
| INFLAMMATION | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| B Cell | therapeutic_target | cell_type | 0.60 |
| Rb | therapeutic_target | protein | 0.60 |
| App | therapeutic_target | protein | 0.60 |
| B Cell | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CD14 | therapeutic_target | gene | 0.60 |
| MRPS31 | associated_with | gene | 0.60 |
| TIMMDC1 | associated_with | gene | 0.60 |
| FBXO7 | associated_with | gene | 0.60 |
| BCS1L | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| INFLAMMATION | associated_with | gene | 0.60 |
| LYRM7 | associated_with | gene | 0.60 |
| IMMUNE INFILTRATION | associated_with | gene | 0.60 |
| MITOCHONDRIA | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||