Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MRPS31: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MRPS31 |
| Key Genes/Proteins | TIMMDC1, FBXO7, BCS1L, PGS1, LYRM7, MITOCHONDRIA |
| Related Diseases | Septic Cardiomyopathy, Als, Cardiovascular, ALS, Inflammation |
Knowledge base pages for this entity
graph TD
MRPS31["MRPS31"]
MRPS31 -.biomarker for.-> Septic_Cardiomyopathy["Septic Cardiomyopathy"]
MRPS31 -->|"target for"| Als["Als"]
MRPS31 -->|"target for"| CD14["CD14"]
MRPS31 -->|"target for"| B_Cell["B Cell"]
MRPS31 -->|"target for"| Rb["Rb"]
MRPS31 -->|"target for"| App["App"]
CD14 -->|"target for"| MRPS31| Target | Relation | Type | Str |
|---|---|---|---|
| Septic Cardiomyopathy | biomarker_for | disease | 0.85 |
| Als | therapeutic_target | disease | 0.65 |
| Cardiovascular | associated_with | disease | 0.65 |
| ALS | associated_with | disease | 0.65 |
| Inflammation | associated_with | disease | 0.65 |
| Cardiomyopathy | associated_with | disease | 0.65 |
| Als | associated_with | disease | 0.65 |
| TIMMDC1 | associated_with | gene | 0.60 |
| FBXO7 | associated_with | gene | 0.60 |
| BCS1L | associated_with | gene | 0.60 |
| PGS1 | associated_with | gene | 0.60 |
| LYRM7 | associated_with | gene | 0.60 |
| MITOCHONDRIA | associated_with | gene | 0.60 |
| AND | associated_with | gene | 0.60 |
| HUB GENES | associated_with | gene | 0.60 |
| IMMUNE INFILTRATION | associated_with | gene | 0.60 |
| CD14 | associated_with | gene | 0.60 |
| B Cell | associated_with | cell_type | 0.60 |
| INFLAMMATION | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| CD14 | therapeutic_target | gene | 0.60 |
| B Cell | therapeutic_target | cell_type | 0.60 |
| Rb | therapeutic_target | protein | 0.60 |
| App | therapeutic_target | protein | 0.60 |
| RIPK2 | expressed_in | gene | 0.60 |
| UHRF1 | expressed_in | gene | 0.60 |
| necroptosis | participates_in | pathway | 0.60 |
| MAPK signaling | participates_in | pathway | 0.60 |
| B Cell | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CD14 | therapeutic_target | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| TIMMDC1 | associated_with | gene | 0.60 |
| INFLAMMATION | associated_with | gene | 0.60 |
| LYRM7 | associated_with | gene | 0.60 |
| PGS1 | associated_with | gene | 0.60 |
| CD14 | associated_with | gene | 0.60 |
| BCS1L | associated_with | gene | 0.60 |
| FBXO7 | associated_with | gene | 0.60 |
| ABCA7 | expressed_in | gene | 0.60 |
| ARF1 | expressed_in | gene | 0.60 |
| ATG7 | expressed_in | gene | 0.60 |
| E2F2 | expressed_in | gene | 0.60 |
| ELAVL1 | expressed_in | gene | 0.60 |
| G6PD | expressed_in | gene | 0.60 |
| GRID2 | expressed_in | gene | 0.60 |
| MAP | expressed_in | gene | 0.60 |
| MAPK | expressed_in | gene | 0.60 |
| MAPK7 | expressed_in | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||