SENESCENT CELLS

Understanding Entity Pages

This page aggregates everything SciDEX knows about SENESCENT CELLS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    SENESCENT_CELLS["SENESCENT CELLS"]
    SENESCENT_CELLS -->|"upregulates"| Pro_survival_Networks["Pro-survival Networks"]
    SENESCENT_CELLS -->|"develops"| SASP["SASP"]
    SENESCENT_CELLS -->|"inhibits"| Apoptosis["Apoptosis"]
    SENESCENT_CELLS -->|"contributes to"| Age_related_Chronic_Diseases["Age-related Chronic Diseases"]
    SENESCENT_CELLS -->|"inhibits"| Hematopoietic_Stem_Cells["Hematopoietic Stem Cells"]
    SENESCENT_CELLS -->|"target for"| chronic_kidney_disease["chronic kidney disease"]
    SENESCENT_CELLS -->|"promotes"| skin_aging["skin aging"]
    SENESCENT_CELLS -->|"contributes to"| Aging["Aging"]
    Abt263["Abt263"] -->|"targets"| SENESCENT_CELLS
    Senolytics["Senolytics"] -->|"targets"| SENESCENT_CELLS
    Senolytic_Drugs["Senolytic Drugs"] -->|"targets"| SENESCENT_CELLS
    ABT263["ABT263"] -->|"targets"| SENESCENT_CELLS
    Hesc_Exos["Hesc-Exos"] -->|"modulates"| SENESCENT_CELLS
    senescent_cell_anti_apoptotic_["senescent cell anti-apoptotic pathways"] -.prevents.-> SENESCENT_CELLS
    senolytics["senolytics"] -->|"treats"| SENESCENT_CELLS
    Total_Body_Irradiation["Total-Body Irradiation"] -->|"causes"| SENESCENT_CELLS