EFNB1

Understanding Entity Pages

This page aggregates everything SciDEX knows about EFNB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

EFNB1 is a gene implicated in neurodegeneration research. Key relationships include: interacts with, activates, implicated in. Associated with AD, ALI, Aging. Connected to 50 entities in the SciDEX knowledge graph.

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graph TD
    EFNB1["<b>EFNB1</b>"]
    Cancer{"Cancer"}
    EFNB1 -->|"associated with"| Cancer
    Carcinoma{"Carcinoma"}
    EFNB1 -->|"interacts with"| Carcinoma
    Ms{"Ms"}
    EFNB1 -->|"interacts with"| Ms
    Tumor{"Tumor"}
    EFNB1 -->|"interacts with"| Tumor
    Longevity{"Longevity"}
    EFNB1 -->|"therapeutic target"| Longevity
    Aging{"Aging"}
    EFNB1 -->|"therapeutic target"| Aging
    EFNB1 -->|"therapeutic target"| Ms
    Cardiac{"Cardiac"}
    EFNB1 -->|"therapeutic target"| Cardiac
    EFNB1 -->|"activates"| Carcinoma
    Osteoporosis{"Osteoporosis"}
    EFNB1 -->|"therapeutic target"| Osteoporosis
    EFNB1 -->|"causes"| Cancer
    EFNB1 -->|"activates"| Aging
    TP53["TP53"]
    TP53 -->|"interacts with"| EFNB1
    ERK["ERK"]
    ERK -->|"interacts with"| EFNB1
    EPHB4["EPHB4"]
    EPHB4 -->|"interacts with"| EFNB1
    AKT["AKT"]
    AKT -->|"interacts with"| EFNB1
    ERCC1["ERCC1"]
    ERCC1 -->|"therapeutic target"| EFNB1
    TP53 -->|"causes"| EFNB1
    SRC["SRC"]
    SRC -->|"interacts with"| EFNB1
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"activates"| EFNB1
    P21["P21"]
    P21 -->|"activates"| EFNB1
    ERCC1 -->|"activates"| EFNB1
    EXERCISE["EXERCISE"]
    EXERCISE -->|"activates"| EFNB1
    AND["AND"]
    AND -->|"interacts with"| EFNB1
    style EFNB1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0