concept

SLC16A3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC16A3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

46Connections

0Hypotheses

0Analyses

33Outgoing

13Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	SLC16A3
Key Genes/Proteins	MCT4, SLC16A10, JUN, SLC16 FAMILY, AND, SLC16A2
Related Diseases	Cancer, ALS, Als
Related Pathways	Glycolysis

Wiki Pages (3)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    SLC16A3["SLC16A3"]
    SLC16A3 -->|"encodes"| MCT4["MCT4"]
    SLC16A3 -->|"involved_in"| ENERGY_METABOLISM["ENERGY METABOLISM"]
    SLC16A3 -->|"transports"| Cancer["Cancer"]
    SLC16A3 -->|"expressed in"| ALS["ALS"]
    SLC16A3 -->|"expressed in"| Als["Als"]
    SLC16A3 -->|"transports"| SLC16A10["SLC16A10"]
    SLC16A3 -->|"transports"| JUN["JUN"]
    AMPK["AMPK"] -->|"expressed in"| SLC16A3
    AND["AND"] -->|"expressed in"| SLC16A3
    ASTROCYTES["ASTROCYTES"] -->|"expressed in"| SLC16A3
    SLC16A10 -->|"target for"| SLC16A3
    SLC16A2["SLC16A2"] -->|"target for"| SLC16A3
    MCT8["MCT8"] -->|"target for"| SLC16A3

Outgoing (33)

Target	Relation	Type	Str
MCT4	encodes	protein	1.00
MCT4	associated_with	protein	1.00
ENERGY METABOLISM	involved_in	entity	0.85
Cancer	transports	disease	0.65
ALS	expressed_in	disease	0.65
Cancer	therapeutic_target	disease	0.65
Als	expressed_in	disease	0.65
SLC16A10	transports	gene	0.60
JUN	transports	gene	0.60
SLC16 FAMILY	transports	gene	0.60
AND	transports	gene	0.60
SLC16A2	transports	gene	0.60
SLC16A1	transports	gene	0.60
CANCER	transports	gene	0.60
Glycolysis	expressed_in	pathway	0.60
ASTROCYTES	expressed_in	gene	0.60
PKM2	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
SLC16A2	therapeutic_target	gene	0.60
MCT8	therapeutic_target	gene	0.60
SLC16A10	therapeutic_target	gene	0.60
Rb	transports	protein	0.60
App	therapeutic_target	protein	0.60
Rb	expressed_in	protein	0.60
oxidative stress response	participates_in	pathway	0.60
YWHAZ	interacts_with	gene	0.60
Thalamus	expressed_in	brain_region	0.55
Hypothalamus	expressed_in	brain_region	0.55
Astrocyte	expressed_in	cell_type	0.55
Neuron	expressed_in	cell_type	0.55
Alzheimer's disease	activates	disease	0.55
unfolded protein response	participates_in	pathway	0.55
astrocytes	expressed_in	cell_type	0.55

Incoming (13)

Source	Relation	Type	Str
AMPK	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
ASTROCYTES	expressed_in	gene	0.60
SLC16A10	therapeutic_target	gene	0.60
SLC16A2	therapeutic_target	gene	0.60
MCT8	therapeutic_target	gene	0.60
SLC16A1	associated_with	gene	0.60
SLC16A1	implicated_in	gene	0.60
MCT1	implicated_in	gene	0.60
MCT1	associated_with	gene	0.55
MCT1	activates	gene	0.55
RNA	activates	gene	0.55
SLC16A1	activates	gene	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found