SORT1

Understanding Entity Pages

This page aggregates everything SciDEX knows about SORT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

SORT1 is a gene implicated in neurodegeneration research. Key relationships include: regulates, interacts with, associated with. Associated with Als, Alzheimer, Ms. Connected to 16 entities in the SciDEX knowledge graph.

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graph TD
    SORT1["<b>SORT1</b>"]
    Ms{"Ms"}
    SORT1 -->|"regulates"| Ms
    Alzheimer{"Alzheimer"}
    SORT1 -->|"associated with"| Alzheimer
    Als{"Als"}
    SORT1 -->|"interacts with"| Als
    APOPTOSIS["APOPTOSIS"]
    SORT1 -->|"regulates"| APOPTOSIS
    Apoptosis(["Apoptosis"])
    SORT1 -->|"regulates"| Apoptosis
    Immune_Response(["Immune Response"])
    SORT1 -->|"regulates"| Immune_Response
    ENDOSOMES["ENDOSOMES"]
    SORT1 -->|"interacts with"| ENDOSOMES
    NEK7["NEK7"]
    SORT1 -->|"interacts with"| NEK7
    neurodegeneration["neurodegeneration"]
    SORT1 -->|"implicated in"| neurodegeneration
    ATP1A1["ATP1A1"]
    ATP1A1 -->|"regulates"| SORT1
    RAB11B["RAB11B"]
    RAB11B -->|"regulates"| SORT1
    AMBRA1["AMBRA1"]
    AMBRA1 -->|"regulates"| SORT1
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"associated with"| SORT1
    APOE["APOE"]
    APOE -->|"associated with"| SORT1
    RAB7A["RAB7A"]
    RAB7A -->|"interacts with"| SORT1
    IGF2R["IGF2R"]
    IGF2R -->|"interacts with"| SORT1
    style SORT1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0