Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TCEB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | TCEB1 |
| Key Genes/Proteins | ELOC, VHL, CUL3 |
| Related Diseases | Clear-Cell Renal Cell Carcinoma, Carcinoma, Cancer, Als, Tumor |
| Related Pathways | Pi3K, Akt, Mtor, Dna Methylation |
graph TD
TCEB1["TCEB1"]
TCEB1 -->|"interacts"| ELOC["ELOC"]
TCEB1 -->|"expressed in"| Carcinoma["Carcinoma"]
TCEB1 -->|"expressed in"| Cancer["Cancer"]
TCEB1 -->|"regulates"| Als["Als"]
TCEB1 -->|"expressed in"| Tumor["Tumor"]
TCEB1 -->|"causes"| ALS["ALS"]
PI3K["PI3K"] -->|"expressed in"| TCEB1
MTOR["MTOR"] -->|"expressed in"| TCEB1
DNA["DNA"] -->|"expressed in"| TCEB1
NRF2["NRF2"] -->|"expressed in"| TCEB1
KEAP1["KEAP1"] -->|"expressed in"| TCEB1
P53["P53"] -->|"expressed in"| TCEB1
AKT["AKT"] -->|"expressed in"| TCEB1
CUL3["CUL3"] -->|"expressed in"| TCEB1| Target | Relation | Type | Str |
|---|---|---|---|
| ELOC | interacts_with | protein | 0.90 |
| Clear-Cell Renal Cell Carcinoma | associated_with | disease | 0.85 |
| Carcinoma | expressed_in | disease | 0.65 |
| Cancer | expressed_in | disease | 0.65 |
| Als | regulates | disease | 0.65 |
| Tumor | expressed_in | disease | 0.65 |
| ALS | causes | disease | 0.65 |
| Als | causes | disease | 0.65 |
| Cancer | methylates | disease | 0.65 |
| VHL | interacts_with | gene | 0.64 |
| Pi3K | expressed_in | pathway | 0.60 |
| Akt | expressed_in | pathway | 0.60 |
| Mtor | expressed_in | pathway | 0.60 |
| Dna Methylation | expressed_in | pathway | 0.60 |
| CUL3 | expressed_in | gene | 0.60 |
| KEAP1 | expressed_in | gene | 0.60 |
| P53 | expressed_in | gene | 0.60 |
| CANCER | expressed_in | gene | 0.60 |
| VHL | causes | gene | 0.60 |
| RNA | expressed_in | gene | 0.60 |
| AND | expressed_in | gene | 0.60 |
| MTOR | expressed_in | gene | 0.60 |
| HIF | causes | gene | 0.60 |
| PI3K | expressed_in | gene | 0.60 |
| DNA | expressed_in | gene | 0.60 |
| NRF2 | expressed_in | gene | 0.60 |
| DNA | methylates | gene | 0.60 |
| RNA | methylates | gene | 0.60 |
| Dna Methylation | methylates | pathway | 0.60 |
| Mtor | methylates | pathway | 0.60 |
| P53 | methylates | protein | 0.60 |
| App | expressed_in | protein | 0.60 |
| VHL | regulates | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PI3K | expressed_in | gene | 0.60 |
| MTOR | expressed_in | gene | 0.60 |
| DNA | expressed_in | gene | 0.60 |
| NRF2 | expressed_in | gene | 0.60 |
| KEAP1 | expressed_in | gene | 0.60 |
| P53 | expressed_in | gene | 0.60 |
| AKT | expressed_in | gene | 0.60 |
| CUL3 | expressed_in | gene | 0.60 |
| VHL | regulates | gene | 0.60 |
| HIF | causes | gene | 0.60 |
| VHL | causes | gene | 0.60 |
| CANCER | expressed_in | gene | 0.60 |
| RNA | expressed_in | gene | 0.60 |
| HIF | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||