UNC5C

Understanding Entity Pages

This page aggregates everything SciDEX knows about UNC5C: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Gene encoding a netrin receptor involved in axon guidance, synaptic plasticity, and Alzheimer's disease susceptibility

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graph TD
    UNC5C["<b>UNC5C</b>"]
    UNC5C_PROTEIN["UNC5C_PROTEIN"]
    UNC5C -->|"encodes"| UNC5C_PROTEIN
    Neurodegeneration{"Neurodegeneration"}
    UNC5C -->|"associated with"| Neurodegeneration
    Alzheimer{"Alzheimer"}
    UNC5C -->|"associated with"| Alzheimer
    Oxidative_Stress(["Oxidative Stress"])
    UNC5C -->|"associated with"| Oxidative_Stress
    Amyloid(["Amyloid"])
    UNC5C -->|"activates"| Amyloid
    ALZHEIMER["ALZHEIMER"]
    UNC5C -->|"associated with"| ALZHEIMER
    NEURODEGENERATION["NEURODEGENERATION"]
    UNC5C -->|"associated with"| NEURODEGENERATION
    AND["AND"]
    UNC5C -->|"associated with"| AND
    AMYLOID["AMYLOID"]
    UNC5C -->|"activates"| AMYLOID
    OXIDATIVE_STRESS["OXIDATIVE STRESS"]
    UNC5C -->|"associated with"| OXIDATIVE_STRESS
    Neuron["Neuron"]
    UNC5C -->|"expressed in"| Neuron
    neurodegeneration["neurodegeneration"]
    UNC5C -->|"implicated in"| neurodegeneration
    AMYLOID -->|"activates"| UNC5C
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"associated with"| UNC5C
    OXIDATIVE_STRESS -->|"associated with"| UNC5C
    ALZHEIMER -->|"associated with"| UNC5C
    style UNC5C fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0