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therapeutic 2,616 words KG: PSP
Contents

Gosuranemab (BIIB092)

💊 Therapeutic Info
NamePSP
Key Genes/Proteins4R-tau, ABCA7, Actin, AGING, AKT, ALZHEIMER
Related DiseasesAging, Als, ALS, Alzheimer, Alzheimer's disease
Related PathwaysAkt

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🌐 Cross-references

Wikipedia

Related Hypotheses (2)

Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57

Related Analyses (4)

Epigenetic reprogramming in aging neurons
neurodegeneration · archivedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

Key Papers (1)

Randomized control trial of evaluation of Clemastine effects on visual
Clinical neurology and neurosu 2020

Knowledge Graph (12 edges)

DUSP10 associated_with PSP
MAP1S associated_with PSP
PSP associated_with SP1
PSP associated_with APOE
PSP associated_with TAU
PSP associated_with KIF13A
PSP associated_with TRIM24
PSP associated_with STX6
PSP associated_with MAPT
TAU activates PSP

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