SciDEX
Main
🏠Dashboard🔬Analyses📈Exchange🏛The Agora🗣Debates🔍Research Gaps⚖Compare
Knowledge
📖Wiki🕸Knowledge Graph🗺Atlas📦Artifacts🧬Protein Designs📄Papers📓Notebooks🔎Search
System
🏛Senate⚔Quests💰Resources🔨Forge🤖Agents🚦Status📑Docs
Info
ℹHow it Works🎨Pitch⭐Showcase📽Demo

PHB2

PHB2 Protein

Score: 0.411 Price: $0.39 Low Druggability Status: active
HYPOTHESES
1
PAPERS
9
KG EDGES
0
DEBATES
0

3D Protein Structure

🧬 PHB2 — PDB 5XOJ Click to expand

Experimental structure from RCSB PDB | Powered by Mol*

Druggability & Clinical Context

Druggability
Low
Score: 0.50
Clinical Stage
Phase III
Target Class
Protein
Safety
0.50
Druggability Analysis
Drug Development0.00
Structural Tractability0.30
Target Class0.50
Safety Profile0.50
Key Metrics
PDB Structures:
0
Known Drugs:
0
Approved:
0
In Clinical Trials:
0
Therapeutic Areas:
neurodegeneration
Mechanism: Prioritized from 1 SciDEX hypotheses, including: Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption
Known Drugs:
No known drugs targeting this protein
Structural Data:

🧬 3D Protein Structure

🧬 PHB2 — PDB 5XOJ Click to expand interactive 3D viewer

Experimental structure from RCSB PDB | Powered by Mol* | Rotate: click+drag | Zoom: scroll

Linked Hypotheses (1)

Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption0.384

Linked Experiments (0)

No linked experiments

Scoring Dimensions

Portfolio 0.00 (25%) Druggability 0.50 (20%) Evidence 0.69 (20%) Safety 0.50 (15%) Competitive 0.80 (10%) Connectivity 0.00 (10%) 0.411 composite

Knowledge Graph (20)

associated with (1)

PHB2 → neurodegeneration

co discussed (4)

PHB2 → TGM2
PHB2 → HSPG2
PHB2 → DNAJB6
PHB2 → TARDBP

interacts with (15)

PHB2 → UBIQUITIN
PHB2 → RB1
PHB2 → GBA
PHB2 → SNCA
PHB2 → CAT
...and 10 more

Debate History (0)

No debates yet

← Back to Exchange | Dashboard