| Gene Symbol | CACNA1G |
| Full Name | Calcium Voltage-Gated Channel Subunit Alpha1 G |
| Chromosome | 17q22 |
| Protein Type | Ion Channel |
| Target Class | Ion Channel |
| Function | The CACNA1G gene encodes the α1G subunit that forms the pore of the T-type (low-voltage activated) calcium channel (CaV3.1). |
| Mechanism of Action | Small molecule blocker of T-type calcium channel activity |
| Druggability | High (0.90) |
| Clinical Stage | Approved |
| Molecular Weight | 262 kDa |
| Pathways | Synaptic function / plasticity |
| UniProt ID | O43497 |
| NCBI Gene ID | 8912 |
| Ensembl ID | ENSG00000006283 |
| GeneCards | CACNA1G |
| Human Protein Atlas | CACNA1G |
| Associated Diseases | Ataxia, Autism, Epilepsy, Huntington's disease, SCA42ND, SCHIZOPHRENIA |
| Known Drugs/Compounds | Nnc-55-0396, SAK3 |
| Interactions | KMT2A, ASXL1, COX6A2, ARID1A, LEF1, WNT3A |
| SciDEX Target | View Target Profile (8 clinical trials) |
| SciDEX Hypotheses | Sleep Spindle-Synaptic Plasticity Enhancement |
| KG Connections | 302 knowledge graph edges |
| Databases | GeneCardsHPASTRING |