gene 1,009 words KG: AURKA
Contents

AURKA Gene

🧬 Gene Info
Gene SymbolAURKA
Full NameAurora Kinase A
Chromosome20q13.2
Protein TypeSerine/Threonine Kinase
Functionencodes a serine/threonine kinase essential for mitotic entry, centrosome maturation, and spindle assembly[@giet2010].
Primary Expressioncertain post-mitotic tissues:
Molecular Weight46 kDa
Amino Acids403 aa
PathwaysCell Cycle, Lipid Metabolism, Pi3K/Akt
UniProt IDO14965
NCBI Gene ID6790
Ensembl IDENSG00000087586
OMIM603072
GeneCardsAURKA
Human Protein AtlasAURKA
Associated DiseasesAlzheimer, Autoimmune, Cancer, Drug Resistance, Gastric Cancer
InteractionsActin, AGING, AKT, APC, AUTOPHAGY, BCL-2
KG Connections156 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

AURKA regulates FOXP1
EGF inhibits AURKA
IGF1 inhibits AURKA
PI3K inhibits AURKA
AURKA inhibits BCL2
FOXP1 regulates AURKA
UBIQUITIN activates AURKA
AURKA upregulates Survivin
AURKA activates UBIQUITIN
ISG15 associated_with AURKA

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