gene 725 words KG: FOXP1 2026-03-24
kind:genesection:genesstate:published
Contents

FOXP1 Gene

🧬 Gene Info
Gene SymbolFOXP1
Chromosome3p13
Protein TypeTranscription Factor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionembryonic brain
Molecular Weight65 kDa
Amino Acids583 aa
Exons23
PathwaysCell Cycle, Complement, Oxidative Stress, Proteasome, Ubiquitin-Proteasome
UniProt IDP0CBB3
OMIM613670
GeneCardsFOXP1
Human Protein AtlasFOXP1
Full nameForkhead Box P1
Protein583 aa
Associated DiseasesALS, Autism, Diabetes
Known Drugs/Compoundsquercetin
InteractionsNLRP3, UBIQUITIN, AURKA, CDKN1A, STAT3, HDAC3
KG Connections153 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Transcriptional Autophagy-Lysosome Coupling
Score: 0.66
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.48
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (4)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: activates
FOXA2 — Forkhead Box A2
gene · KG edge: associated_with
FOS Gene
gene · KG edge: activates
CRH Gene
gene · KG edge: biomarker_for

Knowledge Graph (12 edges)

FOXP1 regulates DNAJB1
FOXP1 activates NLRP3
FOXP1 therapeutic_target TERT
FOXP1 therapeutic_target BRCA2
FOXP1 associated_with FOXM1
FOXP1 associated_with FOXP4
FOXP1 associated_with FOXO4
FOXP1 associated_with FOXO1
FOXP1 associated_with FOXP2
FOXP1 activates UBIQUITIN