| Gene Symbol | UCHL1 |
| Chromosome | 4p14 |
| Protein Type | Enzyme |
| Function | is a highly abundant neuronal deubiquitinating enzyme that constitutes 1-5% of total brain protein. |
| Primary Expression | Cytoplasmic, enriched in axons and synaptic terminals |
| Subcellular Localization | Cytoplasmic, enriched in axons and synaptic terminals |
| Molecular Weight | 24.8 kDa |
| Amino Acids | 223 aa |
| Exons | 9 |
| Pathways | Angiogenesis, Autophagy, Ferroptosis, Glycolysis, Neural Stem Cell Maintenance |
| GeneCards | UCHL1 |
| Human Protein Atlas | UCHL1 |
| Gene location | 4p14 (human) |
| Protein length | 230 amino acids |
| Molecular weight | 24,824 Da |
| Associated Diseases | Ataxia, Ms, Neurodegenerative Diseases, Traumatic Brain Injury, neurodegeneration |
| Interactions | GFAP, TMEM119, NFL, NRF2, KEAP1, UBIQUITIN |
| KG Connections | 183 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |