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Cell: GABAergic Neuron Vulnerability
cell
541 words
KG: GABA
2026-03-24
kind:cell-type
section:cell-types
state:published
Contents
GABAergic Neuron Vulnerability
🧫
Cell Type Info
Cell Type
GABAergic Neuron Vulnerability
Key Pathways
GABAergic Signaling
Associated Diseases
ALS
,
Als
,
Alzheimer
,
Alzheimer'S Disease
,
Amyotrophic Lateral Sclerosis
,
Ataxia
Related Genes
LC3
,
SLC6A13
Linked Hypotheses
122 hypotheses
Knowledge Graph
Related Hypotheses (13)
APOE-Dependent Autophagy Restoration
Score: 0.61
Circadian-Synchronized Proteostasis Enhancement
Score: 0.58
TFEB-Independent Autophagy Bypass
Score: 0.51
Cell-Type Specific TFEB Modulation
Score: 0.48
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.40
TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.40
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.38
Age-Dependent Complement C4b Upregulation Drives Synaptic Vu
Score: 0.47
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.44
Oligodendrocyte White Matter Vulnerability
Score: 0.40
Show 8 more
Related Analyses (14)
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · failed
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · failed
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · failed
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived
Cell type vulnerability in Alzheimer's Disease (SEA-AD data)
neurodegeneration · failed
Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · completed
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Show 9 more
Related Experiments (7)
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · proposed · Score: 0.90
Trehalose-induced lysosomal changes and TFEB activation
exploratory · proposed · Score: 0.90
Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90
Functional validation of trehalose effects on misfolded prot
exploratory · proposed · Score: 0.85
P2RY12-MTOR pathway interaction in VSMCs
exploratory · proposed · Score: 0.85
iPSC-NPC transplantation in ICH animal model
validation · proposed · Score: 0.85
Show 2 more
Knowledge Graph (12 edges)
GABA
co_discussed
JNK
GABA
co_discussed
LC3
GABA
co_discussed
LRRK2
GABA
co_discussed
MTOR
GABA
co_discussed
ULK1
GABA
co_discussed
HISTONE
GABA
co_discussed
ISCHEMIA
GABA
co_discussed
HTT
GABA
co_discussed
MITOCHONDRIA
GABA
co_discussed
MITOPHAGY