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Cell: Globus Pallidus External Segment Neurons
cell
1,455 words
KG: GABA
2026-03-24
kind:cell-type
section:cell-types
state:published
Contents
Globus Pallidus External Segment Neurons
🧫
Cell Type Info
Cell Type
Globus Pallidus External Segment Neurons
Key Pathways
GABAergic Signaling
Associated Diseases
ALS
,
Als
,
Alzheimer
,
Alzheimer'S Disease
,
Amyotrophic Lateral Sclerosis
,
Ataxia
Related Genes
LC3
,
SLC6A13
Linked Hypotheses
126 hypotheses
Knowledge Graph
Related Hypotheses (10)
APOE-Dependent Autophagy Restoration
Score: 0.61
Circadian-Synchronized Proteostasis Enhancement
Score: 0.58
TFEB-Independent Autophagy Bypass
Score: 0.51
Cell-Type Specific TFEB Modulation
Score: 0.48
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.40
TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.40
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.41
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.38
Show 5 more
Related Analyses (9)
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between neurons and glia
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Cell type vulnerability in Alzheimer's Disease (SEA-AD data)
neurodegeneration · failed
Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · completed
Show 4 more
Related Experiments (20)
Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Levodopa-Induced Dyskinesias Mechanism — Experiment Design
validation · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40
Oligodendrocyte-Myelin Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Proteasome-Ubiquitin System Dysfunction Validation in Parkin
clinical · proposed · Score: 0.40
Protein Aggregation Kinetic Validation Results
validation · proposed · Score: 0.40
Purinergic Signaling Dysfunction Validation in Parkinson's D
clinical · proposed · Score: 0.40
Regulated Necrosis Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Stress Granule Dysfunction Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
Experiment Validation: In vitro ThT Assay
validation · proposed · Score: 0.40
iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · proposed · Score: 0.90
Trehalose-induced lysosomal changes and TFEB activation
exploratory · proposed · Score: 0.90
Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90
Functional validation of trehalose effects on misfolded prot
exploratory · proposed · Score: 0.85
P2RY12-MTOR pathway interaction in VSMCs
exploratory · proposed · Score: 0.85
iPSC-NPC transplantation in ICH animal model
validation · proposed · Score: 0.85
Show 15 more
Knowledge Graph (12 edges)
GABA
co_discussed
JNK
GABA
co_discussed
LC3
GABA
co_discussed
LRRK2
GABA
co_discussed
MTOR
GABA
co_discussed
ULK1
GABA
co_discussed
HISTONE
GABA
co_discussed
ISCHEMIA
GABA
co_discussed
HTT
GABA
co_discussed
MITOCHONDRIA
GABA
co_discussed
MITOPHAGY