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cell 874 words KG: GABA
Contents

Globus Pallidus Internus (GPi) Neurons

🧫 Cell Type Info
Cell TypeGABA
Key PathwaysGABAergic Signaling
Associated DiseasesALS, Als, Alzheimer, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis, Ataxia
Related GenesATG, DNA, GABA, GABARAP, HDAC3, LC3
Linked Hypotheses507 hypotheses

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🌐 Cross-references

Wikipedia

Related Hypotheses (9)

APOE-Dependent Autophagy Restoration
Score: 0.89Circadian-Synchronized Proteostasis Enhancement
Score: 0.74The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78Senescent Cell Mitochondrial DNA Release
Score: 0.74Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53

Related Analyses (9)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archivedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedCell type vulnerability in Alzheimer's Disease (SEA-AD data)
neurodegeneration · archived

Related Experiments (20)

Experiment Validation: In vitro ThT Assay
validation · proposed · Score: 0.40Oligodendrocyte-Myelin Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40Proteasome-Ubiquitin System Dysfunction Validation in Parkin
clinical · proposed · Score: 0.40Protein Aggregation Kinetic Validation Results
validation · proposed · Score: 0.40Purinergic Signaling Dysfunction Validation in Parkinson's D
clinical · proposed · Score: 0.40

Knowledge Graph (12 edges)

GABA associated_with MTOR
GABA associated_with TFEB
AKT associated_with GABA
BACE1 associated_with GABA
TAU associated_with GABA
GABA associated_with neuroinflammation
GABA associated_with serotonin
GABA associated_with GABAergic neurons
GABA interacts_with GABARAP
FLCN interacts_with GABA

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