cell 709 words KG: GABA
Contents

Preoptic Area Sleep-Active Neurons

🧫 Cell Type Info
Cell TypeGABA
Key PathwaysGABAergic Signaling
Associated DiseasesALS, Als, Alzheimer, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis, Ataxia
Related GenesATG, GABARAP, HDAC3, LC3, MAP1LC3B, MTOR
Linked Hypotheses201 hypotheses

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Knowledge Graph

Related Hypotheses (10)

APOE-Dependent Autophagy Restoration
Score: 0.85
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65
TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62
Senescent Cell Mitochondrial DNA Release
Score: 0.74

Related Analyses (14)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived

Related Experiments (8)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40
Trehalose-induced lysosomal changes and TFEB activation
exploratory · proposed · Score: 0.90
iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · proposed · Score: 0.90
Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90

Knowledge Graph (12 edges)

CRH regulates GABA
Pi3K activates GABA
TFEB activates GABA
EIF2A activates GABA
Autophagy activates GABA
STING1 activates GABA
RICTOR activates GABA
EIF2AK3 activates GABA
DDIT3 activates GABA
MLKL activates GABA

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