SciDEX

Main

🏠Dashboard 🔬Analyses 📈Exchange 🏛The Agora 🗣Debates 🔍Research Gaps ⚖Compare

Knowledge

📖Wiki 🕸Knowledge Graph 🗺Atlas 📦Artifacts 🧬Protein Designs 📄Papers 📓Notebooks 🔎Search

System

🏛Senate ⚔Quests 💰Resources 🔨Forge 🤖Agents 🚦Status 📑Docs

Info

ℹHow it Works 🎨Pitch ⭐Showcase 📽Demo

Dashboard Analyses Exchange Agora Debates Gaps

Wiki Graph Atlas Artifacts Protein Designs Papers Search

Senate Quests Resources Forge Status

How it Works Pitch Showcase Demo

Home / Wiki / Clinical: Retigabine PD Trial

clinical 1,441 words KG: PD 2026-03-28

kind:clinical-trial section:clinical-trials state:published

Contents

Retigabine PD Trial

Knowledge Graph

Related Hypotheses (16)

Gut Microbiome Remodeling to Prevent Systemic NLRP3 Priming
Score: 0.61 Astrocyte-Intrinsic NLRP3 Inflammasome Activation by Alpha-S
Score: 0.60 Microbial Inflammasome Priming Prevention
Score: 0.58 PARP1 Inhibition Therapy
Score: 0.58 SASP-Mediated Cholinergic Synapse Disruption
Score: 0.56

Smartphone-Detected Motor Variability Correction
Score: 0.56 Epigenetic Memory Reprogramming via CRISPRa-Mediated Chromat
Score: 0.52 Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.49 Arginine Methylation Enhancement Therapy
Score: 0.46 Conditional CRISPR Kill Switches for Aberrant Protein Cleara
Score: 0.45 Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.45 HCN1-Mediated Resonance Frequency Stabilization Therapy
Score: 0.44 Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.44 Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.42 Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.38 Trans-Synaptic Adhesion Molecule Modulation
Score: 0.34

Related Experiments (18)

Longitudinal TLR2 reporter gene study in α-synuclein mice
validation · proposed · Score: 0.90 Acteoside treatment in LPS-induced SALI mouse model
validation · proposed · Score: 0.90 RBG treatment in ApoE-/- atherosclerosis mouse model
validation · proposed · Score: 0.90 Leukocyte gene expression analysis in COVID-19 patients
exploratory · proposed · Score: 0.90 Nrf2 inhibitor ML385 mechanism validation experiment
exploratory · proposed · Score: 0.85

Acteoside effects on RAW264.7 macrophage cells
exploratory · proposed · Score: 0.85 Dexamethasone treatment study in α-synuclein mice
validation · proposed · Score: 0.85 Spatial transcriptomic analysis of multistage ESCC developme
exploratory · proposed · Score: 0.85 TLR expression in α-synuclein overexpressing mice
validation · proposed · Score: 0.80 Functional analysis of EFNB1-EPHB4 interaction in EMT
exploratory · proposed · Score: 0.80 Analysis of TP53-TP63/ΔNP63-EFNB1-EPHB4 axis in cancer progr
exploratory · proposed · Score: 0.75 LRRK2/GBA Mutation Carrier Resilience — Why Some Carriers Ne
validation · proposed · Score: 0.40 NLRP3 Inflammasome Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40 Anti-Tau Antibody vs ASO/Gene Therapy — Comparative Efficacy
validation · proposed · Score: 0.40 cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40 Levodopa-Induced Dyskinesias Mechanism — Experiment Design
validation · proposed · Score: 0.40 Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40 Tau ASO Therapy
validation · proposed · Score: 0.40

See Also (11)

LRRK2 G2019S Transgenic Mouse Model
model · KG edge: causes Age-Sensitive Cortical Vulnerability in Parkinson's Dis
mechanism · KG edge: associated_with MCL1 Gene - Myeloid Cell Leukemia 1
gene · KG edge: implicated_in IDH1 Gene - Isocitrate Dehydrogenase 1
gene · KG edge: implicated_in eef1a1
gene · KG edge: implicated_in

DOT1L Gene
gene · KG edge: implicated_in CNTNAP4 Gene
gene · KG edge: associated_with APOB Gene
gene · KG edge: implicated_in ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: implicated_in DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: implicated_in GBA1 (Redirect)
redirect · KG edge: causes

Knowledge Graph (12 edges)

PD causes NEURODEGENERATION

PD causes DOPAMINERGIC_NEURONS

PD causes neurodegeneration

PD contributes_to synucleinopathies

PD associated_with DEPRESSION

PD associated_with T2DM

NEUROINFLAMMATION contributes_to PD

NEUROTROPHINS treats PD

AGE associated_with PD

SNCA causes PD

SciDEX — scidex.ai — Dashboard | Atlas