gene 1,208 words KG: CTSL
Contents

CTSL Gene

🧬 Gene Info
Gene SymbolCTSL
Full NameCathepsin L
Chromosome9q21.33
Protein TypeProtease
Functionencodes a lysosomal cysteine protease that plays crucial roles in protein degradation, antigen processing, and extracellular matrix remodeling.
Primary ExpressionUbiquitous; highest in liver
Amino Acids333 aa
Exons8
PathwaysAutophagy
UniProt IDP07711
NCBI Gene ID1517
Ensembl IDENSG00000135047
OMIM116830
GeneCardsCTSL
Human Protein AtlasCTSL
Associated DiseasesNeurodegeneration, Parkinson
InteractionsACTB, AGING, AIF1, ALZHEIMER, ALZHEIMER'S DISEASE, APOC1
KG Connections137 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

BNIP3 regulates CTSL
BCL2 regulates CTSL
CTSL therapeutic_target FOXO3
CTSL regulates PIK3R1
CTSL regulates BECN1
CTSL regulates STAT3
CTSL regulates CTSB
CTSL regulates HIF1A
CTSL therapeutic_target FOXO1
CTSL regulates PIK3C3

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