gene 1,313 words KG: CD44
Contents

CD44 - Cell Surface Glycoprotein

🧬 Gene Info
Gene SymbolCD44
Full NameCell Surface Glycoprotein
AliasesPage for CD44
Chromosome11p13
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight95 kDa
Amino Acids341 aa
Exons19
PathwaysNF-κB, TGF-β
NCBI Gene ID2115452
Ensembl IDENSG00000026508
GeneCardsCD44
Human Protein AtlasCD44
Associated DiseasesAging, Als, Alzheimer, Cardiac, dementia
InteractionsADAM10, AKT, ALS, ALZHEIMER, ALZHEIMER DISEASE, ALZHEIMER'S DISEASE
SciDEX HypothesesCD44-SPP1 Axis Precision Targeting
Hyaluronidase Treatment Disrupts Perivascular Infl
KG Connections747 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

Hypothesis 2: GPNMB-CD44 Axis as Anti-inflammatory Pathway
Score: 0.77
CD44-Mediated Src/PI3K/Akt Signaling Cascade
Score: 0.47
CD44-SPP1 Axis Precision Targeting
Score: 0.00
Hyaluronidase Treatment Disrupts Perivascular Inflammatory N
Score: 0.00

Knowledge Graph (12 edges)

LEF1 therapeutic_target CD44
FGF20 therapeutic_target CD44
BRG1 therapeutic_target CD44
NRCAM therapeutic_target CD44
NOTCH2 therapeutic_target CD44
EP300 therapeutic_target CD44
CTNNB1 therapeutic_target CD44
NEUROD1 therapeutic_target CD44
MYC therapeutic_target CD44
VEGFA therapeutic_target CD44

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