gene 663 words KG: FGF20 2026-03-22
kind:genesection:genesstate:published
Contents

FGF20 Gene

🧬 Gene Info
Gene SymbolFGF20
Full NameFibroblast Growth Factor 20
Chromosome8p21.3
FunctionFGF20 is a member of the FGF family of growth factors, which are involved in various developmental and regenerative processes.
Primary Expressionthe brain, particularly in the substantia nigra
Molecular Weight23 kDa
PathwaysPI3K, MAPK
UniProt IDQ9NP95
NCBI Gene ID56844
Ensembl IDENSG00000078579
OMIM605830
GeneCardsFGF20
Human Protein AtlasFGF20
Associated Diseasesneurodegeneration
KG Connections111 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (9)

Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.48
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.45
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.44
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam
Score: 0.62

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Packard Center for ALS Research
institution · KG edge: therapeutic_target
FGF18 Gene
gene · KG edge: therapeutic_target
EP300 Gene
gene · KG edge: therapeutic_target
DKK1 — Dickkopf WNT Signaling Pathway Inhibitor 1
gene · KG edge: therapeutic_target
CTNNB1 — Catenin Beta 1
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

FGF20 therapeutic_target BRG1
FGF20 therapeutic_target NRCAM
FGF20 therapeutic_target NOTCH2
FGF20 therapeutic_target EP300
FGF20 therapeutic_target CTNNB1
FGF20 therapeutic_target NEUROD1
FGF20 therapeutic_target MYC
FGF20 therapeutic_target VEGFA
FGF20 therapeutic_target ABCB1
FGF20 therapeutic_target FOXM1