| Gene Symbol | CHI3L1 |
| Full Name | Chitinase 3-Like 1 |
| Aliases | Chitinase 3-like Protein 1 |
| Chromosome | 1q32.1 |
| Protein Type | Hydrolase |
| Function | CHI3L1 is a member of the glycosyl hydrolase family 18 but lacks enzymatic activity. |
| Primary Expression | hippocampus, cortex, and basal ganglia
- Cell Types: Primarily microglia and astrocytes
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| Molecular Weight | 40 kDa |
| Amino Acids | 383 aa |
| Pathways | NF-κB signaling |
| UniProt ID | P36222 |
| NCBI Gene ID | 1116 |
| Ensembl ID | ENSG00000133048 |
| GeneCards | CHI3L1 |
| Human Protein Atlas | CHI3L1 |
| Associated Diseases | Als, Alzheimer, Fibrosis, Inflammation, Neuroinflammation, neurodegeneration |
| Known Drugs/Compounds | hygromycin B |
| Interactions | AQP4, GBM, STAT3, RAGE, APP, JAK1 |
| SciDEX Hypotheses | Integrated Biomarker Panel for Therapeutic Window |
| KG Connections | 360 knowledge graph edges |
| Databases | GeneCardsHPASTRING |