| Gene Symbol | DDX58 |
| Full Name | DEAD-Box Helicase 58 |
| Chromosome | 9q34.3 |
| Protein Type | Receptor |
| Function | DDX58 (DEAD-Box Helicase 58), commonly known as RIG-I (Retinoic Acid-Inducible Gene I), is a cytoplasmic pattern recognition receptor (PRR) that detects viral RNA and initiates antiviral immune respon |
| Primary Expression | Ubiquitous, high in immune cells and brain |
| Pathways | Interferon Signaling |
| UniProt ID | O95786 |
| NCBI Gene ID | 23586 |
| Ensembl ID | ENSG00000107201 |
| OMIM | 609561 |
| GeneCards | DDX58 |
| Human Protein Atlas | DDX58 |
| Alternative Names | RIG-I, RIGI, RLR-1 |
| Protein Class | DEAD-box helicase, Pattern Recognition Receptor |
| Associated Diseases | neurodegeneration |
| Interactions | BAX, CSF1, STAT1, BECN1, HNRNPA1 |
| KG Connections | 20 knowledge graph edges |
| Databases | GeneCardsHPASTRING |