gene 1,604 words KG: NTN3 2026-03-27
kind:genesection:genesstate:published
Contents

NTN3 Gene

🧬 Gene Info
Gene SymbolNTN3
Full NameNetrin 3
Chromosome16p13.3
Protein TypeReceptor
FunctionLike other netrins, NTN3 exerts its effects through binding to two main receptor families
Primary Expressionthe adult brain and may have roles in synaptic plasticity and repair
Molecular Weight~71 kDa
Amino Acids641 aa
UniProt IDQ9Y2I2
NCBI Gene ID4904
Ensembl IDENSG00000118445
OMIM603389
GeneCardsNTN3
Human Protein AtlasNTN3
Protein Length641 amino acids
Associated DiseasesAD, ALI, Als, Alzheimer, Alzheimer's disease, ILD
InteractionsSNRNP70, TARDBP, TAU, NTN1, Rb, AMYLOID
KG Connections49 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Cryptic Exon Silencing Restoration
Score: 0.46
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Cross-Seeding Prevention Strategy
Score: 0.45
Glycine-Rich Domain Competitive Inhibition
Score: 0.43

Related Analyses (4)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (8)

Packard Center for ALS Research
institution · KG edge: associated_with
Accelerating Medicines Partnership for Alzheimer's Dise
institution · KG edge: implicated_in
Alzheimer Indonesia
institution · KG edge: associated_with
NTN1 Gene - Netrin 1
gene · KG edge: interacts_with
JUN Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

NTN3 interacts_with SNRNP70
NTN3 interacts_with TARDBP
NTN3 interacts_with TAU
NTN3 interacts_with NTN1
NTN3 expressed_in JUN
NTN3 interacts_with Rb
NTN3 expressed_in Alzheimer
NTN3 expressed_in Als
NTN3 expressed_in Endocytosis
NTN3 expressed_in Complement