| Gene Symbol | SNRNP70 |
| Full Name | Small nuclear ribonucleoprotein 70kDa |
| Chromosome | 19q13.33 |
| Function | SNRNP70 (U1-70K, RNPU1L) is a core component of the U1 small nuclear ribonucleoprotein (snRNP) complex, which plays an essential role in pre-mRNA splicing |
| Molecular Weight | 70kDa |
| UniProt ID | [P08621](https://www.uniprot.org/uniprot/P08621) |
| Ensembl ID | ENSG00000106462 |
| GeneCards | SNRNP70 |
| Human Protein Atlas | SNRNP70 |
| Early Recognition | The U1 snRNP recognizes the 5' splice site before the 3' splice site is recognized. |
| Cross-intron Recognition | SNRNP70 helps bridge the 5' and 3' splice sites together. |
| Catalysis | The assembled spliceosome catalyzes two transesterification reactions to remove introns. |
| Recycling | SNRNP70 is released and recycled for new splicing events. |
| Associated Diseases | AD, ALI, Als, Alzheimer, Alzheimer's disease, ILD |
| Interactions | NTN3, TARDBP, TAU, NTN1, DNA, PTN |
| KG Connections | 57 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |