gene 1,559 words KG: SLC2A2 2026-03-28
kind:genesection:genesstate:published
Contents

SLC2A2 Gene

🧬 Gene Info
Gene SymbolSLC2A2
Full NameSLC2A2
AliasesGLUT2
Protein TypeGene
FunctionUnlike high-affinity glucose transporters such as GLUT1 (SLC2A1) or GLUT3 (SLC2A3), GLUT2 has a relatively low affinity for glucose (Km ~15-20 mM), which makes it well-suited for tissues where glucose
Primary Expressiontissues critical for metabolic homeostasis, including the liver, pancreas, intestine, kidney, and specific brain regions
NCBI Gene IDSearch NCBI
GeneCardsSLC2A2
Human Protein AtlasSLC2A2
Associated Diseasesneurodegeneration
InteractionsSLC2A1, COX4I1, GSK3B, NRXN3, PRKAA1, BDNF
KG Connections57 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (6)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
CYP46A1 Overexpression Gene Therapy
Score: 0.63
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

CREB-independent Neuronal Survival Pathways
mechanism · KG edge: protects_against
Packard Center for ALS Research
institution · KG edge: protects_against
DLG4 Gene
gene · KG edge: protects_against
PRKAA1
gene · KG edge: inhibits
PDHA1
gene · KG edge: inhibits

Knowledge Graph (12 edges)

SLC2A2 inhibits SLC2A1
SLC2A2 inhibits COX4I1
SLC2A2 inhibits GSK3B
SLC2A2 protects_against AKT
SLC2A2 protects_against SOD2
SLC2A2 inhibits NRXN3
SLC2A2 inhibits PRKAA1
SLC2A2 inhibits BDNF
SLC2A2 inhibits SOD1
SLC2A2 inhibits NLGN2