gene 1,559 words KG: SLC2A2
Contents

SLC2A2 Gene

🧬 Gene Info
Gene SymbolSLC2A2
AliasesGLUT2
Protein TypeGene
FunctionUnlike high-affinity glucose transporters such as GLUT1 (SLC2A1) or GLUT3 (SLC2A3), GLUT2 has a relatively low affinity for glucose (Km ~15-20 mM), which makes it well-suited for tissues where glucose
Primary Expressiontissues critical for metabolic homeostasis, including the liver, pancreas, intestine, kidney, and specific brain regions
GeneCardsSLC2A2
Human Protein AtlasSLC2A2
Associated Diseasesneurodegeneration
InteractionsABCC8, Bdnf, BDNF, CAT, COX4I1, CYCS
KG Connections56 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (6)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.83
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Hypocretin-Neurogenesis Coupling Therapy
Score: 0.69

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: protects_against
Neurodegeneration
disease · KG edge: protects_against
Genes
index · KG edge: inhibits
BDNF Gene
gene · KG edge: inhibits
CAT — Catalase
gene · KG edge: inhibits

Knowledge Graph (12 edges)

NRXN3 inhibits SLC2A2
PDHA1 inhibits SLC2A2
BDNF inhibits SLC2A2
PRKAA1 inhibits SLC2A2
SOD2 protects_against SLC2A2
SOD1 inhibits SLC2A2
NLGN2 inhibits SLC2A2
PSD95 protects_against SLC2A2
CYCS inhibits SLC2A2
CAT inhibits SLC2A2

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