gene 2,395 words KG: HERC2
Contents

HERC2 Gene

🧬 Gene Info
Gene SymbolHERC2
Full NameHECT and RLD Domain Containing E3 Ubiquitin Protein Ligase 2
Chromosome15q13.1
Protein FamilyHERC family (HECT-type E3 ubiquitin ligases)
Functionis a hallmark of aging and neurodegenerative diseases.
Molecular Weight500 kDa
Amino Acids834 aa
PathwaysmTOR, mtor
UniProt IDQ9Y5K5
NCBI Gene ID8924
Ensembl IDENSG00000128731
OMIM607318
GeneCardsHERC2
Human Protein AtlasHERC2
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsCANCER, INFLAMMATION, JAK2, LC3, STAT3, ULK1
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

STAT3 activates HERC2
JAK2 activates HERC2
HERC2 associated_with UBIQUITIN
HERC2 activates ULK1
HERC2 activates LC3
INFLAMMATION activates HERC2
CANCER activates HERC2
HERC2 activates Tumor
HERC2 activates Hepatocellular Carcinoma
HERC2 activates Cancer

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