gene 2,395 words KG: HERC2 2026-03-28
kind:genesection:genestopic:alzheimerstopic:parkinsonsstate:published
Contents

HERC2 Gene

🧬 Gene Info
Gene SymbolHERC2
Full NameHECT and RLD Domain Containing E3 Ubiquitin Protein Ligase 2
Chromosome15q13.1
Protein FamilyHERC family (HECT-type E3 ubiquitin ligases)
Functionis a hallmark of aging and neurodegenerative diseases.
Molecular Weight500 kDa
Amino Acids834 aa
PathwaysmTOR, mtor
UniProt IDQ9Y5K5
NCBI Gene ID8924
Ensembl IDENSG00000128731
OMIM607318
GeneCardsHERC2
Human Protein AtlasHERC2
Length4,834 amino acids
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsULK1, LC3, STAT3, JAK2, INFLAMMATION, CANCER
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph