gene 3,051 words KG: MCL1
Contents

MCL1 Gene - Myeloid Cell Leukemia 1

🧬 Gene Info
Gene SymbolMCL1
Full NameMyeloid Cell Leukemia 1
Chromosome1q21.2
Functionencodes a critical anti-apoptotic protein of the BCL2 family that plays essential roles in regulating mitochondrial outer membrane permeabilization (MOMP), cellular survival, and mitochondrial dyna...
Molecular Weight37 kDa
Amino Acids350 aa
PathwaysNF-κB
UniProt ID[Q07820](https://www.uniprot.org/uniprot/Q07820)
Ensembl IDENSG00000143384
GeneCardsMCL1
Human Protein AtlasMCL1
Associated DiseasesAD, ALI, Als, Alzheimer, AMI
InteractionsACHE, AD, APOB, APOE, APOPTOSIS, App
KG Connections345 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

IDH1 therapeutic_target MCL1
VEGFA therapeutic_target MCL1
MDM4 therapeutic_target MCL1
APOB therapeutic_target MCL1
SF3B1 therapeutic_target MCL1
MET therapeutic_target MCL1
SMARCA4 therapeutic_target MCL1
TERT therapeutic_target MCL1
JUN therapeutic_target MCL1
EEF1A1 therapeutic_target MCL1

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