gene 1,092 words KG: MUTYH
Contents

MUTYH Gene

🧬 Gene Info
Gene SymbolMUTYH
Chromosome1p34.2
Protein TypeEnzyme
FunctionWithout MUTYH, the mispaired adenine becomes fixed as a G:C to T:A mutation during replication.
Primary Expressionall tissues, with high expression in: - Brain: cerebral cortex, hippocampus, cerebellum -
Molecular Weight52 kDa
Amino Acids479 aa
Exons16
PathwaysDNA Repair
GeneCardsMUTYH
Human Protein AtlasMUTYH
Associated DiseasesAls, cancer, neurodegeneration
InteractionsATM, COMPLEMENT, CTC1, DNA, LMNA, MDM2
KG Connections48 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

TREX1 interacts_with MUTYH
VCP interacts_with MUTYH
NEIL1 interacts_with MUTYH
POLD1 interacts_with MUTYH
POT1 interacts_with MUTYH
MRE11 interacts_with MUTYH
MUTYH interacts_with SAMHD1
MUTYH interacts_with NBS1
MUTYH interacts_with LMNA
MUTYH interacts_with WRN

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