concept

NINJ2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NINJ2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

24Connections

0Hypotheses

0Analyses

17Outgoing

7Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	NINJ2
Key Genes/Proteins	EGR1, AND, PDGFRB, PI3K, IGF1, IGF1R
Related Diseases	Liver Fibrosis, Fibrosis

Wiki Pages (1)

Knowledge base pages for this entity

IGF1R Gene

gene · 983 words

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Pathway Diagram

graph TD
    NINJ2["NINJ2"]
    NINJ2 -->|"interacts"| IGF1R["IGF1R"]
    NINJ2 -->|"contributes to"| Liver_Fibrosis["Liver Fibrosis"]
    NINJ2 -->|"activates"| Fibrosis["Fibrosis"]
    NINJ2 -->|"activates"| EGR1["EGR1"]
    NINJ2 -->|"activates"| AND["AND"]
    NINJ2 -->|"activates"| PDGFRB["PDGFRB"]
    NINJ2 -->|"activates"| PI3K["PI3K"]
    NINJ2 -->|"activates"| IGF1["IGF1"]
    AKT["AKT"] -->|"activates"| NINJ2
    IGF1R -->|"activates"| NINJ2
    PDGF["PDGF"] -->|"activates"| NINJ2
    IGF1 -->|"activates"| NINJ2
    PDGFRB -->|"activates"| NINJ2
    PI3K -->|"activates"| NINJ2
    EGR1 -->|"activates"| NINJ2

Outgoing (17)

Target	Relation	Type	Str
Liver Fibrosis	contributes_to	disease	0.95
Fibrosis	activates	disease	0.65
EGR1	activates	gene	0.60
AND	activates	gene	0.60
PDGFRB	activates	gene	0.60
PI3K	activates	gene	0.60
IGF1	activates	gene	0.60
IGF1R	activates	gene	0.60
T Cell	activates	cell_type	0.60
Hepatocyte	activates	cell_type	0.60
Insulin	activates	protein	0.60
Cytokine	activates	protein	0.60
Rb	activates	protein	0.60
Pdgf	activates	protein	0.60
Akt	activates	protein	0.60
Igf	activates	protein	0.60
T Cell	expressed_in	cell_type	0.55

Incoming (7)

Source	Relation	Type	Str
AKT	activates	gene	0.60
IGF1R	activates	gene	0.60
PDGF	activates	gene	0.60
IGF1	activates	gene	0.60
PDGFRB	activates	gene	0.60
PI3K	activates	gene	0.60
EGR1	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found