Contents

PAK1 Gene

🧬 Gene Info

Gene Symbol	PAK1
Full Name	P21 (RAC1) Activated Kinase 1
Chromosome	11q13.5
Protein Type	Serine/Threonine Kinase
Function	encodes a serine/threonine kinase that serves as a critical downstream effector of the Rho GTPases Rac1 and Cdc42.
Primary Expression	the brain, particularly in the hippocampus and cerebral cortex, where it plays essential roles in dendritic spine morphogenesis, synapse formation, an
Molecular Weight	65 kDa
Amino Acids	545 aa
Exons	15
Pathways	Apoptosis, Autophagy, Camp Signaling, Circadian Rhythm, Invasion
UniProt ID	[Q13153](https://www.uniprot.org/uniprot/Q13153)
Ensembl ID	ENSG00000149269
OMIM	602590
GeneCards	PAK1
Human Protein Atlas	PAK1
Associated Diseases	Als, Cancer, Encephalitis, Inflammation, Multiple Sclerosis
Interactions	AND, APOPTOSIS, ATG12, ATG16L1, ATG5, AUTOPHAGY
KG Connections	146 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Knowledge Graph