| Gene Symbol | TMEM106B |
| Aliases | Transmembrane Protein 106B |
| Chromosome | 7p21.3 |
| Protein Family | Type II lysosomal transmembrane protein family |
| Function | is a 323-amino acid type II lysosomal transmembrane protein encoded by the TMEM106B gene on chromosome 7p21. |
| Primary Expression | Late endosomes and lysosomes |
| Molecular Weight | 30.3 kDa |
| Amino Acids | 274 aa |
| Exons | 9 |
| Pathways | Autophagy, endosome-lysosome function |
| UniProt ID | Q9NUM4 |
| GeneCards | TMEM106B |
| Human Protein Atlas | TMEM106B |
| Strategy | Mechanism |
| Antisense Oligonucleotides | Reduce TMEM106B expression |
| Associated Diseases | AGING, ALS, Alzheimer, Alzheimer's disease |
| Interactions | NFL, TAU, TREM2, GRN, PTK2B, LRP1 |
| KG Connections | 411 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |