Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RS7529220: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | RS7529220 |
| Key Genes/Proteins | ALZHEIMER'S DISEASE, ASTROCYTES, PLEC, C1Q, GENES, MICROGLIA |
| Related Diseases | Heart Failure, Cardiovascular, Alzheimer, Als, Ms |
graph TD
RS7529220["RS7529220"]
RS7529220 -->|"expressed in"| Alzheimer["Alzheimer"]
RS7529220 -->|"expressed in"| ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
RS7529220 -->|"expressed in"| PLEC["PLEC"]
RS7529220 -->|"expressed in"| C1Q["C1Q"]
RS7529220 -->|"expressed in"| GENES["GENES"]
RS7529220 -->|"expressed in"| ALZHEIMER["ALZHEIMER"]
RS7529220 -->|"expressed in"| AND["AND"]
RS7529220 -->|"expressed in"| Macrophage["Macrophage"]
ALZHEIMER -->|"expressed in"| RS7529220
ALZHEIMER_S_DISEASE -->|"expressed in"| RS7529220
AND -->|"expressed in"| RS7529220
GENES -->|"expressed in"| RS7529220
PLEC -->|"expressed in"| RS7529220
C1Q -->|"expressed in"| RS7529220| Target | Relation | Type | Str |
|---|---|---|---|
| Heart Failure | associated_with | disease | 0.65 |
| Cardiovascular | associated_with | disease | 0.65 |
| Alzheimer | expressed_in | disease | 0.65 |
| Als | associated_with | disease | 0.65 |
| Ms | associated_with | disease | 0.65 |
| ALS | associated_with | disease | 0.65 |
| ALZHEIMER'S DISEASE | expressed_in | gene | 0.60 |
| ASTROCYTES | associated_with | gene | 0.60 |
| PLEC | expressed_in | gene | 0.60 |
| C1Q | expressed_in | gene | 0.60 |
| GENES | expressed_in | gene | 0.60 |
| MICROGLIA | associated_with | gene | 0.60 |
| ALZHEIMER | expressed_in | gene | 0.60 |
| Macrophage | associated_with | cell_type | 0.60 |
| Microglia | associated_with | cell_type | 0.60 |
| Astrocyte | associated_with | cell_type | 0.60 |
| RNA | associated_with | gene | 0.60 |
| AND | expressed_in | gene | 0.60 |
| Cardiomyocyte | associated_with | cell_type | 0.60 |
| Actin | associated_with | protein | 0.60 |
| App | associated_with | protein | 0.60 |
| Macrophage | expressed_in | cell_type | 0.55 |
| Astrocyte | expressed_in | cell_type | 0.55 |
| Microglia | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| MICROGLIA | associated_with | gene | 0.60 |
| ALZHEIMER | expressed_in | gene | 0.60 |
| ASTROCYTES | associated_with | gene | 0.60 |
| ALZHEIMER'S DISEASE | expressed_in | gene | 0.60 |
| AND | expressed_in | gene | 0.60 |
| GENES | expressed_in | gene | 0.60 |
| PLEC | expressed_in | gene | 0.60 |
| C1Q | expressed_in | gene | 0.60 |
| GENETIC LOCI | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||