gene 1,892 words KG: SLC6A4
Contents

SLC6A4 Gene — Serotonin Transporter

🧬 Gene Info
Gene SymbolSLC6A4 (SERT, 5HTT)
AliasesSerotonin Transporter
Chromosome17q11.2
Functionis a membrane protein that mediates the reuptake of serotonin (5-hydroxytryptamine, 5-HT) from the synaptic cleft back into presynaptic neurons.
Molecular Weight63 kDa
Amino Acids630 aa
Exons14
PathwaysApoptosis, Epigenetic, Mapk, autophagy pathway
UniProt IDP31645
NCBI Gene ID6532
Ensembl IDENSG00000108576
Associated DiseasesAddiction, Als, Alzheimer, Alzheimer's disease
InteractionsActin, ALZHEIMER, ALZHEIMER'S DISEASE, AND, APOE, APOPTOSIS
KG Connections325 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Serotonergic 5-HT1A/1B Agonism for Neuroprotection
Score: 0.42

Knowledge Graph (12 edges)

SLC6A4 associated_with TRD
MAOB associated_with SLC6A4
GABRA1 associated_with SLC6A4
CHAT associated_with SLC6A4
HMGCR associated_with SLC6A4
OPRM1 associated_with SLC6A4
SLC30A8 associated_with SLC6A4
COMT associated_with SLC6A4
NBEA associated_with SLC6A4
HTR2C associated_with SLC6A4

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