gene 861 words KG: HTR2C 2026-03-24
kind:genesection:genesstate:published
Contents

HTR2C Gene

🧬 Gene Info
Gene SymbolHTR2C
Full Name5-Hydroxytryptamine Receptor 2C
ChromosomeXq24
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe central nervous system
Molecular Weight70 kDa
PathwaysMAPK signaling
UniProt IDP28335
NCBI Gene ID3358
Ensembl IDENSG00000140048
OMIM312861
GeneCardsHTR2C
Human Protein AtlasHTR2C
Protein ClassG Protein-Coupled Receptor (Class A)
Associated DiseasesAlzheimer, Alzheimer'S Disease, Anxiety, Autism, Bipolar
InteractionsDRD1, CACNA1B, GABRA1, GRM5, GRIK4, SLC6A2
KG Connections139 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (10)

Noradrenergic-Tau Propagation Blockade
Score: 0.51
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Alzheimer Indonesia
institution · KG edge: associated_with
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: associated_with
CYP3A4 — Cytochrome P450 3A4
gene · KG edge: associated_with
CYP2D6 — Cytochrome P450 2D6
gene · KG edge: associated_with
COMT Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

HTR2C associated_with SLC30A8
HTR2C associated_with ADRA2A
HTR2C associated_with BCHE
HTR2C associated_with SLC6A2
HTR2C associated_with SLC6A3
HTR2C associated_with ABCB1
HTR2C associated_with SLC6A4
HTR2C associated_with GSTP1
HTR2C associated_with CYP3A4
HTR2C associated_with ABCG2