| Gene Symbol | CHAT |
| Chromosome | 10q11.23 |
| Function | The reaction mechanism involves |
| Subcellular Localization | the cytoplasm of presynaptic nerve terminals, but also associates with synaptic vesicles for regulated neurotransmitter |
| Molecular Weight | 68-82 kDa |
| Amino Acids | 748 aa |
| Exons | 14 |
| Pathways | Apoptosis, Cell Cycle |
| GeneCards | CHAT |
| Human Protein Atlas | CHAT |
| Gene Length | ~46 kb |
| Protein Class | Acetyltransferase (choline O-acetyltransferase) |
| Primary Localization | Cytoplasm of cholinergic neurons |
| Disease Associations | Alzheimer's disease, congenital myasthenic syndrome, PD |
| Region | Function |
| Associated Diseases | Als, Alzheimer, Alzheimer'S Disease, Anxiety, Dementia |
| Interactions | Rab5a, BDNF, TRKB, NGF, SYP, SLC22A1 |
| SciDEX Hypotheses | Sensory-Motor Circuit Cross-Modal Compensation |
| KG Connections | 339 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |