| Gene Symbol | SLC6A4 (SERT, 5HTT) |
| Aliases | SERT, 5HTT, SAT2, hSERT |
| Chromosome | 17q11.2 |
| Function | is a membrane protein that mediates the reuptake of serotonin (5-hydroxytryptamine, 5-HT) from the synaptic cleft back into presynaptic neurons. |
| Molecular Weight | ~70 kDa |
| Amino Acids | 630 aa |
| Exons | 14 |
| Pathways | Apoptosis, Epigenetic, Mapk, autophagy pathway |
| UniProt ID | P31645 |
| NCBI Gene ID | 6532 |
| Ensembl ID | ENSG00000108576 |
| Uniprot ID | P31645 |
| Protein Length | 630 amino acids |
| Step | Process |
| 1 | Na+ binding to extracellular site |
| Associated Diseases | ALS, Addiction, Alzheimer, Alzheimer'S Disease |
| Interactions | JUN, CASP3, ERK2, RHOT1, STING, SYN1 |
| KG Connections | 320 knowledge graph edges |
| Databases | GeneCardsHPASTRING |