gene 1,243 words KG: NBEA
Contents

NBEA — Neurobeachin

🧬 Gene Info
Gene SymbolNBEA
Full NameNeurobeachin
AliasesBCL8B
Chromosome13q13.3
Protein FamilyBEACH (Beige and Chediak-Higashi) family
FunctionScaffolding protein for protein kinase A, synaptic receptor trafficking
Primary ExpressionBrain (high), heart, lung, testis
Molecular Weight327.4 kDa
Amino Acids2946
Exons58 exons
PathwaysSynaptic plasticity, PKA signaling
UniProt IDQ8NFP9
NCBI Gene ID26045
Ensembl IDENSG00000172915
GeneCardsNBEA
Human Protein AtlasNBEA
Associated DiseasesAlzheimer, Alzheimer'S Disease, Anxiety, Dementia, Depression
InteractionsGENES, PER
KG Connections81 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (12)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
Noradrenergic-Tau Propagation Blockade
Score: 0.51
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56

Related Analyses (2)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Alzheimer Indonesia
institution · KG edge: associated_with
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: associated_with
GABRA1 Gene
gene · KG edge: associated_with
CYP3A4 — Cytochrome P450 3A4
gene · KG edge: associated_with
CYP2D6 — Cytochrome P450 2D6
gene · KG edge: associated_with

Knowledge Graph (12 edges)

NBEA associated_with HTR2C
NBEA associated_with ADRA2A
NBEA associated_with BCHE
NBEA associated_with SLC6A2
NBEA associated_with SLC6A3
NBEA associated_with ABCB1
NBEA associated_with SLC6A4
NBEA associated_with GSTP1
NBEA associated_with CYP3A4
NBEA associated_with ABCG2