gene 963 words KG: SNRNP70
Contents

SNRNP70 Gene

🧬 Gene Info
Gene SymbolSNRNP70
Full NameSmall nuclear ribonucleoprotein 70kDa
Chromosome19q13.33
FunctionSNRNP70 (U1-70K, RNPU1L) is a core component of the U1 small nuclear ribonucleoprotein (snRNP) complex, which plays an essential role in pre-mRNA splicing
Molecular Weight70kDa
UniProt ID[P08621](https://www.uniprot.org/uniprot/P08621)
Ensembl IDENSG00000106462
GeneCardsSNRNP70
Human Protein AtlasSNRNP70
Early RecognitionThe U1 snRNP recognizes the 5' splice site before the 3' splice site is recognized.
Cross-intron RecognitionSNRNP70 helps bridge the 5' and 3' splice sites together.
CatalysisThe assembled spliceosome catalyzes two transesterification reactions to remove introns.
RecyclingSNRNP70 is released and recycled for new splicing events.
Associated DiseasesAD, ALI, Als, Alzheimer, Alzheimer's disease, disease
InteractionsAMYLOID, DNA, NTN1, NTN3, Proteins, PTN
KG Connections54 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

MATR3 Nuclear Body Disruption Impairs RNA Processing Hubs an
Score: 0.80

Knowledge Graph (12 edges)

TARDBP interacts_with SNRNP70
NTN1 interacts_with SNRNP70
SNRNP70 expressed_in JUN
SNRNP70 interacts_with NTN3
SNRNP70 interacts_with TARDBP
JUN associated_with SNRNP70
NTN3 interacts_with SNRNP70
JUN expressed_in SNRNP70
SNRNP70 interacts_with TAU
SNRNP70 associated_with TREM2

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