gene 718 words KG: XRCC1
Contents

XRCC1 Gene

🧬 Gene Info
Gene SymbolXRCC1
Protein TypeScaffold Protein
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionall tissues: - High expression in brain (neurons, glia) - Moderate expression in other proliferating cells - Induced by oxidative stress - Cell type-s
Molecular Weight69 kDa
Amino Acids633 aa
Pathwaysepigenetic regulation, neurotrophin signaling
GeneCardsXRCC1
Human Protein AtlasXRCC1
Associated DiseasesCancer, Fibrosis
InteractionsALDH1A3, AND, App, BDNF, CAMK2A, CANCER
KG Connections58 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (1)

Oligodendrocyte DNA Repair Enhancement Therapy
Score: 0.66

Knowledge Graph (12 edges)

XPG activates XRCC1
SETX activates XRCC1
TDP1 activates XRCC1
PNKP activates XRCC1
FEN1 activates XRCC1
XPF activates XRCC1
XRCC1 activates SETX
XRCC1 activates FEN1
XRCC1 causes TP53
XRCC1 causes CYP2D6

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