gene 2,823 words KG: ZBP1
Contents

ZBP1 (Z-DNA Binding Protein 1)

🧬 Gene Info
Gene SymbolZBP1
Aliasesnecroptosis, PANoptosis
Chromosome6p24.1
Functionis a cytosolic nucleic acid sensor that plays critical roles in innate immune responses, regulated cell death pathways, and inflammation[@takaoka2007; @kuriakose2023].
Molecular Weight46 kDa
Amino Acids429 aa
PathwaysApoptosis, Autophagy, Complement, Epigenetic, Immune Response
UniProt IDQ9H171
NCBI Gene ID23073
Ensembl IDENSG00000185730
GeneCardsZBP1
Human Protein AtlasZBP1
Associated DiseasesAls, Alzheimer, Alzheimer's disease, Atherosclerosis, Inflammation
InteractionsABCG2, Actin, ADAR1, AIM2, ALZHEIMER, AMYLOID
KG Connections395 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Co-translational mRNA localization as a sensor for RNA granu
Score: 0.55

Knowledge Graph (12 edges)

BAX activates ZBP1
DRP1 activates ZBP1
FADD activates ZBP1
NRF2 activates ZBP1
ABCG2 activates ZBP1
ZBP1 activates MFN2
ZBP1 activates GSDMD
ZBP1 activates RIPK1
ZBP1 activates RAB7A
ZBP1 activates CAT

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