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ABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member 2

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slug	genes-abcg2
entity_type	gene
kg_node_id	ABCG2

Linked Artifacts (201)

mentions🧪Synthetic Biology BBB Endothelial Cell Reprogramming70%

mentions🧪APOE Isoform Conversion Therapy70%

mentions🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides70%

mentions🧪APOE4-Selective Lipid Nanoemulsion Therapy70%

see_also📖AMPK (AMP-Activated Protein Kinase)60%

see_also📖ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member 160%

see_also📖BAX Gene60%

see_also📖CAT — Catalase60%

see_also📖DRP1 Gene - Dynamin 1-Like Protein60%

see_also📖FADD Gene60%

see_also📖GSDMD Gene60%

see_also📖mfn260%

see_also📖NRF2 Gene60%

see_also📖RIPK1 Gene60%

see_also📖ZBP1 (Z-DNA Binding Protein 1)60%

see_also📖NRF2 Activator Therapy60%

see_also📖BAX Protein60%

see_also📖DRP1 (Dynamin-Related Protein 1)60%

see_also📖Gasdermin D Protein60%

see_also📖Mitofusin 2 (MFN2)60%

see_also📖nrf260%

see_also📖RIPK1 (Receptor-Interacting Kinase 1)60%

see_also📖Dementia with Lewy Bodies Biomarkers60%

see_also📖Epigenetic Biomarkers in Neurodegenerative Diseases60%

see_also📖Cerebellar Granule Cells in Neurodegenerative Disease60%

see_also📖Cerebellar Neurons in Creutzfeldt-Jakob Disease60%

see_also📖Cerebellar Purkinje Cells60%

see_also📖Pedunculopontine Nucleus Cholinergic Neurons in Lewy Body Di60%

see_also📖Pedunculopontine Nucleus Neurons in Lewy Body Disease60%

see_also📖Spinal Cord Interneurons in Motor Neuron Disease60%

see_also📖Dementia with Lewy Bodies Circuit60%

see_also📖Dementia with Lewy Bodies Diagnostic Methods60%

see_also📖diseases-motoneuron-disease60%

see_also📖Apoptosis in Neurodegeneration60%

see_also📖Epigenetic Clocks in Neurodegeneration — Causal Drivers or P60%

see_also📖Epigenetic Dysregulation in Huntington's Disease — Ther60%

see_also📖Epigenetic Dysregulation Validation in Parkinson's Dise60%

see_also📖Epigenetic Regulation Dysfunction in Alzheimer's and Pa60%

see_also📖Dementia with Lewy Bodies Knowledge Gaps60%

see_also📖ADRA2A Gene60%

see_also📖ADRB2 Gene60%

see_also📖BCHE Gene - Butyrylcholinesterase60%

see_also📖CHAT Gene60%

see_also📖COMT Gene60%

see_also📖CYP2D6 — Cytochrome P450 2D660%

see_also📖CYP3A4 — Cytochrome P450 3A460%

see_also📖GABRA1 Gene60%

see_also📖GSTP1 — Glutathione S-Transferase Pi 160%

see_also📖HMGCR — 3-Hydroxy-3-Methylglutaryl-CoA Reductase60%

see_also📖HTR2C Gene60%

see_also📖MAOB Gene60%

see_also📖nbea60%

see_also📖OPRM1 — Mu-Opioid Receptor60%

see_also📖slc30a860%

see_also📖SLC6A2 — Norepinephrine Transporter60%

see_also📖SLC6A3 Gene60%

see_also📖SLC6A4 Gene — Serotonin Transporter60%

see_also📖Epigenetic Dysregulation Hypothesis in Parkinson's Dise60%

see_also📖Epigenetic-Metabolic Coupling: SIRT1 Activator + NAD+ Precur60%

see_also📖Epigenetic Clock Reversal Therapy for Neurodegeneration Prev60%

see_also📖Alzheimer Indonesia60%

see_also📖Dementia Australia60%

see_also📖dementia-discovery-fund60%

see_also📖Apoptosis Inhibitors for Neurodegeneration — Investment Land60%

see_also📖Epigenetic Therapy in Neurodegeneration: Investment Landscap60%

see_also📖Epigenetic Alterations in Alzheimer's Disease60%

see_also📖Apoptosis Pathway in Neurodegeneration60%

see_also📖Apoptosis Pathways in Alzheimer's Disease60%

see_also📖Apoptosis in Neurodegeneration60%

see_also📖Apoptosis Pathways in Parkinson's Disease60%

see_also📖Cerebrovascular Disease in Neurodegeneration60%

see_also📖cross-disease60%

see_also📖Dementia with Lewy Bodies Mechanistic Pathway60%

see_also📖Epigenetic Alterations in Alzheimer's Disease60%

see_also📖Epigenetic Clocks in Brain Aging60%

see_also📖Epigenetic Dysregulation Comparison Across Neurodegenerative60%

see_also📖Epigenetic Dysregulation in 4R-Tauopathies60%

see_also📖Epigenetic Dysregulation in Neurodegeneration60%

see_also📖Epigenetic Regulation60%

see_also📖Epigenetic Mechanisms in Alzheimer's Disease60%

see_also📖Epigenetic Changes in Progressive Supranuclear Palsy60%

see_also📖IVNS1ABP Mutation: Progeria-Like Disease with Neurological D60%

see_also📖GSTP1 Protein (Glutathione S-Transferase Pi 1)60%

see_also📖Mu-Opioid Receptor Protein60%

see_also📖Epigenetic Reprogramming and Partial Reprogramming in Neurod60%

see_also📖Epigenetic Therapies for Neurodegeneration60%

see_also📖Epigenetic Therapies for Parkinson's Disease60%

see_also📖Tumor Necrosis Factor Alpha (TNF-α) as a Neurodegenerative D60%

see_also📖Tumor Necrosis Factor (TNF)60%

see_also📖ABCA2 Gene - ATP Binding Cassette Subfamily A Member 260%

see_also📖ABCD3 Gene60%

see_also📖ABCG1 Gene60%

see_also📖ATP7A60%

see_also📖slc22a560%

see_also📖Tumor-Derived Cystatin C Enables Amyloid Clearance60%

see_also📖ABCD3 Protein60%

see_also📖RAB7A — RAB7A, Member RAS Oncogene Family60%

see_also📖Genes60%

see_also📖Notch Signaling and Gamma-Secretase Modulators for Alzheimer60%

see_also📖JAK Inhibitors in Parkinson's Disease60%

see_also📖Notch and Gamma-Secretase Modulators for Parkinson's Di60%

see_also📖MTOR (Redirect)60%

see_also📖entities-stat360%

see_also📖mTOR Signaling Dysregulation in Progressive Supranuclear Pal60%

see_also📖AKT1 Gene60%

see_also📖AURKA Gene60%

see_also📖BID — BH3 Interacting Domain Death Agonist60%

see_also📖casp360%

see_also📖CD44 - Cell Surface Glycoprotein60%

see_also📖dr560%

see_also📖MMP9 Gene60%

see_also📖MTOR Gene60%

see_also📖PI3K — Phosphoinositide 3-Kinase60%

see_also📖STAT3 Gene60%

see_also📖VEGF (Vascular Endothelial Growth Factor)60%

see_also📖Notch Signaling Modulation Therapy for Neurodegeneration60%

see_also📖erk-mapk-signaling-neurodegeneration60%

see_also📖HIF Signaling in Neurodegeneration60%

see_also📖JAK-STAT and Cytokine Signaling in 4R-Tauopathies60%

see_also📖JAK-STAT Signaling in Parkinson's Disease60%

see_also📖JAK-STAT Signaling Pathway in Neurodegeneration60%

see_also📖Notch Signaling in Parkinson's Disease60%

see_also📖Notch Signaling in 4R-Tauopathies60%

see_also📖Notch Signaling Pathway in Neurodegeneration60%

see_also📖Notch Signaling in Parkinson's Disease60%

see_also📖Notch Signaling Pathway in Neurodegeneration60%

see_also📖AKT1 Protein (Protein Kinase B Alpha)60%

see_also📖D5 Dopamine Receptor Protein60%

see_also📖JNK (c-Jun N-terminal Kinase) Protein60%

see_also📖MMP9 Protein60%

see_also📖MTOR Protein60%

see_also📖Notch Signaling Modulators for Neurodegeneration60%

mentions🧪Piezoelectric Nanochannel BBB Disruption50%

mentions🧪Metabolic Switch Targeting for A1→A2 Repolarization50%

mentions🧪Serine/Arginine-Rich Protein Kinase Modulation50%

mentions🧪Noradrenergic-Tau Propagation Blockade50%

mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%

mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%

mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%

mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%

mentions🧪Competitive APOE4 Domain Stabilization Peptides50%

mentions🧪APOE Isoform Expression Across Glial Subtypes50%

mentions🧪Biorhythmic Interference via Controlled Sleep Oscillations50%

mentions🧪Mitochondrial-Lysosomal Contact Site Engineering50%

see_also📖BEACoN Study - Biomarker Exploration in Aging, Cognition and50%

see_also📖LX1001 Phase 1/2 Trial (NCT03634007) - Gene Therapy for APOE50%

see_also📖LX1001 Long-Term Follow-up (NCT05400330) - Gene Therapy for 45%

see_also📖nct0550878945%

see_also📖remternetug-anti-amyloid-alzheimers45%

see_also📖UPenn Observational Research Repository (NCT04715399)45%

see_also📖APOE4 (Apolipoprotein E4)45%

mentions🧫cGAS-STING Pathway Validation Study in Parkinson's Dise40%

mentions🧫Epigenetic Dysregulation Validation in Parkinson's Dise40%

mentions🧫Microglial Aging and Immune Memory in Neurodegeneration — Tr40%

mentions🧫Non-Motor Symptom Progression in Parkinson's Disease — 40%

mentions🧫Synaptic Mitochondrial Resilience Enhancement for Parkinson&40%

mentions🔬What are the mechanisms underlying rna binding protein dysre40%

mentions🔬APOE4 differs from APOE3 by C112R causing domain interaction40%

mentions🔬RNA binding protein dysregulation across ALS FTD and AD40%

mentions🔬Analyze circuit-level changes in neurodegeneration using All40%

related🧪APOE Isoform Conversion Therapy40%

mentions🔬What are the mechanisms underlying tdp-43 phase separation t35%

mentions🔬What are the mechanisms underlying astrocyte reactivity subt35%

mentions🔬What are the mechanisms underlying blood-brain barrier trans35%