Ganglioside Rebalancing Therapy

**Mechanistic Foundation** Gangliosides are sialic acid-containing glycosphingolipids that constitute 5-10% of the lipid mass in neuronal membranes, where they serve critical roles in membrane organization, receptor signaling, and neuroprotection. Different ganglioside species (GM1, GD1a, GD1b, GT1b, etc.) create distinct membrane microdomains that regulate synaptic plasticity, calcium signaling, and neurotrophic factor responses. The ganglioside composition of neurons is precisely regulated du...