Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about BRCA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Parp Inhibitor Response | associated_with | phenotype | 0.75 |
| Cancer | expressed_in | disease | 0.65 |
| Als | regulates | disease | 0.65 |
| Cancer | activates | disease | 0.65 |
| HCRTR1 | expressed_in | gene | 0.60 |
| Rb | regulates | protein | 0.60 |
| DOT1L | expressed_in | gene | 0.60 |
| cancer | inhibits | disease | 0.60 |
| KEAP1 | associated_with | gene | 0.60 |
| NRF2 | associated_with | gene | 0.60 |
| cardiovascular disease | associated_with | disease | 0.60 |
| PTPN11 | associated_with | gene | 0.60 |
| BRCA1 | inhibits | gene | 0.60 |
| BRCA1 | interacts_with | gene | 0.60 |
| DNA | activates | gene | 0.60 |
| Ras | activates | protein | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| ubiquitin-proteasome | participates_in | pathway | 0.60 |
| endothelial cells | expressed_in | cell_type | 0.60 |
| benchmark_ot_ad_answer_key:BRCA | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| HCRTR2 | expressed_in | gene | 0.60 |
| CD4 | expressed_in | gene | 0.60 |
| benchmark_ot_ad_answer_key:BRCA | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||