concept

CMTM6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CMTM6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

37Connections

0Hypotheses

0Analyses

25Outgoing

12Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	CMTM6
Key Genes/Proteins	CD68, MICROGLIA, GLIOBLASTOMA, IBA1, GBM, PD-L1
Related Diseases	Glioblastoma, Tumor

Pathway Diagram

graph TD
    CMTM6["CMTM6"]
    CMTM6 -->|"activates"| Glioblastoma["Glioblastoma"]
    CMTM6 -->|"activates"| Tumor["Tumor"]
    CMTM6 -->|"regulates"| microglia["microglia"]
    CMTM6 -->|"expressed in"| CD68["CD68"]
    CMTM6 -->|"expressed in"| MICROGLIA["MICROGLIA"]
    CMTM6 -->|"activates"| GLIOBLASTOMA["GLIOBLASTOMA"]
    CMTM6 -->|"activates"| Macrophage["Macrophage"]
    CMTM6 -->|"expressed in"| Microglia["Microglia"]
    IBA1["IBA1"] -->|"expressed in"| CMTM6
    GBM["GBM"] -->|"expressed in"| CMTM6
    TMEM119["TMEM119"] -->|"expressed in"| CMTM6
    PD_L1["PD-L1"] -->|"inhibits"| CMTM6
    PD_1["PD-1"] -->|"expressed in"| CMTM6
    UBIQUITIN["UBIQUITIN"] -->|"regulates"| CMTM6
    RNA["RNA"] -->|"expressed in"| CMTM6
    CD68 -->|"expressed in"| CMTM6

Outgoing (25)

Target	Relation	Type	Str
Glioblastoma	activates	disease	0.65
Tumor	activates	disease	0.65
microglia	regulates	cell_type	0.60
CD68	expressed_in	gene	0.60
MICROGLIA	expressed_in	gene	0.60
GLIOBLASTOMA	activates	gene	0.60
Macrophage	activates	cell_type	0.60
Microglia	expressed_in	cell_type	0.60
IBA1	expressed_in	gene	0.60
GBM	expressed_in	gene	0.60
PD-L1	inhibits	gene	0.60
TMEM119	expressed_in	gene	0.60
Cytokine	expressed_in	protein	0.60
Ubiquitin	regulates	protein	0.60
App	expressed_in	protein	0.60
ubiquitin-proteasome	participates_in	pathway	0.60
microglia	expressed_in	cell_type	0.60
RNA	expressed_in	gene	0.60
oxidative stress response	participates_in	pathway	0.60
GBM	biomarker_for	gene	0.60
glioblastoma	biomarker_for	disease	0.60
macrophages	expressed_in	cell_type	0.60
IBA1	biomarker_for	gene	0.60
TMEM119	biomarker_for	gene	0.60
Macrophage	expressed_in	cell_type	0.55

Incoming (12)

Source	Relation	Type	Str
IBA1	expressed_in	gene	0.60
GBM	expressed_in	gene	0.60
TMEM119	expressed_in	gene	0.60
PD-L1	inhibits	gene	0.60
PD-1	expressed_in	gene	0.60
UBIQUITIN	regulates	gene	0.60
RNA	expressed_in	gene	0.60
CD68	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
MICROGLIA	expressed_in	gene	0.60
CD68	biomarker_for	gene	0.60
CD274	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found